Phospho-γH2A.X (S139) Polyclonal Antibody | G-AB-12511

Phospho-γH2A.X (S139) Polyclonal Antibody | G-AB-12511 | Gentaur Antibodies

Overview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

Category Type: Phosphorylated antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: H2A.X, H2A/X, H2AX, Histone H2AX, H2AFX, histone H2AX, gamma H2A.X, γH2AX

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 3014

Accession #:

Clonality:

Immunogen: A synthetic phosphorylated peptide around S139 of human γH2A.X (NP_002096.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P16104

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:100 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Phospho-γH2A.X (S139) Polyclonal Antibody DataSheet