Phospho-MAP3K7 (Thr187) Polyclonal Antibody | G-AB-05765

Phospho-MAP3K7 (Thr187) Polyclonal Antibody | G-AB-05765 | Gentaur Antibodies

Overview: Component of a protein kinase Signal Transduction cascade. Mediator of TRAF6 and TGF-beta Signal Transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.

Category Type: Phosphorylated antibody

Research Areas: Cancer, Cardiovascular, Immunology, Signal Transduction

Synonyms: M3K7, MAP3K 7, Map3k7, MEKK7, Mitogen activated protein kinase kinase kinase 7, Mitogen-activated protein kinase kinase kinase 7, TAK1, TGF beta activated kinase 1, TGF-beta-activated kinase 1, TGF1a, Transforming growth factor beta activated kinase 1, Transforming growth factor-beta-activated kinase 1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human Tak1 around the phosphorylation site of Thr187

Clone #:

Conjugation: Unconjugated

Swissprot: O43318

Santa Cruz:

Calculated MW: 67 kDa

Observed MW: 60 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification method: Affinity purification

Application: WB, IHC-p, ELISA

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Phospho-MAP3K7 (Thr187) Polyclonal Antibody DataSheet