Phospho-STAT1 (S727) Polyclonal Antibody | G-AB-12568

Phospho-STAT1 (S727) Polyclonal Antibody | G-AB-12568 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

Category Type: Phosphorylated antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms: CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91, STAT1 alpha, STAT1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 6772

Accession #:

Clonality:

Immunogen: A phospho specific peptide corresponding to residues surrounding S727 of human STAT1

Clone #:

Conjugation: Unconjugated

Swissprot: P42224

Santa Cruz:

Calculated MW: 83 kDa/87 kDa

Observed MW: 87 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:2000 IHC 1:50-1:100 IF 1:100-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Phospho-STAT1 (S727) Polyclonal Antibody DataSheet