Phospho-TrkA (Y490) Polyclonal Antibody | G-AB-12581
Gentaur Antibodies
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Gentaur Antibodies
Phospho-TrkA (Y490) Polyclonal Antibody | G-AB-12581
- SKU:
- G-AB-12581
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
Phospho-TrkA (Y490) Polyclonal Antibody | G-AB-12581 | Gentaur Antibodies
Overview: This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Category Type: Phosphorylated antibody
Research Areas: Cancer, Neuroscience
Synonyms: NTRK1, MTC, TRK, TRK1, TRKA, Trk-A, p140-TrkA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Gene ID: 4914
Accession #:
Clonality:
Immunogen: A phospho specific peptide corresponding to residues surrounding Y490 of human TrkA
Clone #:
Conjugation: Unconjugated
Swissprot: P04629
Santa Cruz:
Calculated MW: 77 kDa/83 kDa/86 kDa/87 kDa
Observed MW: 150 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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