Phospho-TrkA (Y490) Polyclonal Antibody | G-AB-12581

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€236.04 - €477.96
SKU:
G-AB-12581
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human, Mouse
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Phospho-TrkA (Y490) Polyclonal Antibody | G-AB-12581 | Gentaur Antibodies

Overview: This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.

Category Type: Phosphorylated antibody

Research Areas: Cancer, Neuroscience

Synonyms: NTRK1, MTC, TRK, TRK1, TRKA, Trk-A, p140-TrkA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 4914

Accession #:

Clonality:

Immunogen: A phospho specific peptide corresponding to residues surrounding Y490 of human TrkA

Clone #:

Conjugation: Unconjugated

Swissprot: P04629

Santa Cruz:

Calculated MW: 77 kDa/83 kDa/86 kDa/87 kDa

Observed MW: 150 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Phospho-TrkA (Y490) Polyclonal Antibody DataSheet

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