Phospho-ZAP70 (Y319) Polyclonal Antibody | G-AB-12571

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Phospho-ZAP70 (Y319) Polyclonal Antibody | G-AB-12571 | Gentaur Antibodies

Overview: This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated Signal Transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.

Category Type: Phosphorylated antibody

Research Areas: Cancer, Immunology, Signal Transduction, Tags & Cell Markers

Synonyms: ZAP70, ADMIO2, IMD48, SRK, STCD, STD, TZK, ZAP-70

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 7535

Accession #:


Immunogen: A synthetic phosphorylated peptide around Y319 of human ZAP70 (NP_001070.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P43403

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Phospho-ZAP70 (Y319) Polyclonal Antibody DataSheet

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