PNN Polyclonal Antibody | G-AB-01822

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€136.92 - €390.60
SKU:
G-AB-01822
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human, Mouse
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PNN Polyclonal Antibody | G-AB-01822 | Gentaur Antibodies

Overview: Pinin is a desmosomal associated protein involved with the maintenance of cell to cell adhesion of the epithelium. Pinin is a widespread protein and has been shown to play an important role in cell adhesion through its interaction with nuclear complexes. Pinin is also involved in pre-mRNA splicing through its interactions with a C-terminal RS domain of Cyclophilin G, a Moca type nuclear cyclophilin. Pinin becomes nuclear during the early stages of embryonic development and remains so throughout the entire period. Defects or lack of Pinin can be lethal at perinatal stages and causes defects in the cardiac outflow tract, axial skeleton, palate and dorsal dermis.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: 140 kDa nuclear and cell adhesion-related phosphoprotein, Desmosome-associated protein, Domain-rich serine protein, DRS, DRS protein, DRSP, Melanoma metastasis clone A protein, MEMA, Nuclear protein SDK3, Pinin, PININ, PNN, SR like protein, SR-like protein

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_002678

Clonality: Polyclonal

Immunogen: Synthetic peptide of human PNN

Clone #:

Conjugation: Unconjugated

Swissprot: Q9H307

Santa Cruz: sc-74833

Calculated MW:

Observed MW:

Concentration: 1.2 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PNN Polyclonal Antibody DataSheet