PSMB9 Polyclonal Antibody | G-AB-09716

PSMB9 Polyclonal Antibody | G-AB-09716 | Gentaur Antibodies

Overview: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex) . Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology

Synonyms: PSMB9, LMP2, PSMB6i, RING12, beta1i

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 5698

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human PSMB9 (NP_002791.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P28065

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:10-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PSMB9 Polyclonal Antibody DataSheet