PTPRS Polyclonal Antibody | G-AB-12318
- 3 to 5 Working Days
PTPRS Polyclonal Antibody | G-AB-12318 | Gentaur Antibodies
Overview: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.
Category Type: Polyclonal Antibody
Research Areas: Neuroscience, Signal Transduction
Synonyms: PTPRS, PTPSIGMA, R-PTP-S, R-PTP-sigma
Gene ID: 5802
Immunogen: Recombinant fusion protein of human PTPRS (NP_002841.3) .
Calculated MW: 168 kDa/171 kDa/212 kDa/214 kDa/215 kDa/217 kDa
Observed MW: 220 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.