PUM1 Polyclonal Antibody | G-AB-10941
- 3 to 5 Working Days
- Human, Mouse, Rat
PUM1 Polyclonal Antibody | G-AB-10941 | Gentaur Antibodies
Overview: This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Developmental Biology, Stem Cells
Synonyms: PUM1, HSPUM, PUMH, PUMH1, PUML1
Reactivity: Human, Mouse, Rat
Gene ID: 9698
Immunogen: Recombinant fusion protein of human PUM1 (NP_055491.1) .
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IHC, IF
Dilution: IHC 1:50-1:100 IF 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.