PUM1 Polyclonal Antibody | G-AB-10941

PUM1 Polyclonal Antibody | G-AB-10941 | Gentaur Antibodies

Overview: This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Developmental Biology, Stem Cells

Synonyms: PUM1, HSPUM, PUMH, PUMH1, PUML1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 9698

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human PUM1 (NP_055491.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q14671

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:100 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PUM1 Polyclonal Antibody DataSheet