RAD23B Polyclonal Antibody | G-AB-07370

RAD23B Polyclonal Antibody | G-AB-07370 | Gentaur Antibodies

Overview: The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER) . This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG) , which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: RAD23B, HHR23B, HR23B, P58

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 5887

Accession #:

Clonality:

Immunogen: A synthetic peptide of human RAD23B (NP_002865.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P54727

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:100-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

RAD23B Polyclonal Antibody DataSheet