RGR Polyclonal Antibody | G-AB-05026

RGR Polyclonal Antibody | G-AB-05026 | Gentaur Antibodies

Overview: This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively) . Alternative splicing results in multiple transcript variants encoding different isoforms.

Category Type: Polyclonal Antibody

Research Areas: Neuroscience, Signal Transduction

Synonyms: hRGR, Ral GDS related protein, Retinal G protein coupled receptor, RGR-opsin, RP44, RPE retinal G protein coupled receptor

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP001012738

Clonality: Polyclonal

Immunogen: Synthetic peptide of human RGR

Clone #:

Conjugation: Unconjugated

Swissprot: P47804

Santa Cruz:

Calculated MW: 32 kDa

Observed MW: Refer to figures

Concentration: 0.78 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

RGR Polyclonal Antibody DataSheet