RUNX1T1 Polyclonal Antibody | G-AB-09699
Gentaur Antibodies
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Gentaur Antibodies
RUNX1T1 Polyclonal Antibody | G-AB-09699
- SKU:
- G-AB-09699
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
RUNX1T1 Polyclonal Antibody | G-AB-09699 | Gentaur Antibodies
Overview: This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t (8;21) (q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Synonyms: RUNX1T1, AML1-MTG8, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID: 862
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human RUNX1T1 (NP_783554.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: Q06455
Santa Cruz:
Calculated MW: 44 kDa/48 kDa/63 kDa/64 kDa/67 kDa/68 kDa
Observed MW: 67 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB
Dilution: WB 1:200-1:1000
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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