S100B Polyclonal Antibody | G-AB-07213

S100B Polyclonal Antibody | G-AB-07213 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Stem cells

Synonyms: NEF, S100, S100-B, S100beta, S100B, S100 beta

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 6285

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human S100B (NP_006263.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P04271

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

S100B Polyclonal Antibody DataSheet