SAV1 Polyclonal Antibody | G-AB-12463
- 3 to 5 Working Days
- Human, Mouse
SAV1 Polyclonal Antibody | G-AB-12463 | Gentaur Antibodies
Overview: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1) -associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.
Category Type: Polyclonal Antibody
Research Areas: Signal Transduction
Synonyms: SAV1, SAV, WW45, WWP4
Reactivity: Human, Mouse
Gene ID: 60485
Immunogen: Recombinant fusion protein of human SAV1 (NP_068590.1) .
Calculated MW: 44 kDa
Observed MW: 45 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: WB 1:1000-1:4000
Storage: Store at -20°C. Avoid freeze / thaw cycles.