SAV1 Polyclonal Antibody | G-AB-12463

SAV1 Polyclonal Antibody | G-AB-12463 | Gentaur Antibodies

Overview: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1) -associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: SAV1, SAV, WW45, WWP4

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 60485

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human SAV1 (NP_068590.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9H4B6

Santa Cruz:

Calculated MW: 44 kDa

Observed MW: 45 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:1000-1:4000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SAV1 Polyclonal Antibody DataSheet