SEC31A Polyclonal Antibody | G-AB-12356
- 3 to 5 Working Days
- Human, Mouse, Rat
SEC31A Polyclonal Antibody | G-AB-12356 | Gentaur Antibodies
Overview: The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII) . The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13) , and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms.
Category Type: Polyclonal Antibody
Synonyms: SEC31A, ABP125, ABP130, HSPC275, HSPC334, SEC31L1
Reactivity: Human, Mouse, Rat
Gene ID: 22872
Immunogen: Recombinant fusion protein of human SEC31A (NP_055748.2) .
Calculated MW: 56 kDa/105-134 kDa
Observed MW: 165 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: WB 1:1000-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.