SEC31A Polyclonal Antibody | G-AB-12356

SEC31A Polyclonal Antibody | G-AB-12356 | Gentaur Antibodies

Overview: The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII) . The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13) , and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: SEC31A, ABP125, ABP130, HSPC275, HSPC334, SEC31L1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 22872

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human SEC31A (NP_055748.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: O94979

Santa Cruz:

Calculated MW: 56 kDa/105-134 kDa

Observed MW: 165 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:1000-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SEC31A Polyclonal Antibody DataSheet