SERPINB6 Polyclonal Antibody | G-AB-12447
- 3 to 5 Working Days
- Human, Rat
SERPINB6 Polyclonal Antibody | G-AB-12447 | Gentaur Antibodies
Overview: The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin (ov) -serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene.
Category Type: Polyclonal Antibody
Research Areas: Cell Biology
Synonyms: SERPINB6, CAP, DFNB91, MSTP057, PI-6, PI6, PTI, SPI3, serpin B6
Reactivity: Human, Rat
Gene ID: 5269
Immunogen: Recombinant fusion protein of human SERPINB6 (NP_004559.4) .
Calculated MW: 42 kDa
Observed MW: 43 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.