SERPINB6 Polyclonal Antibody | G-AB-12447

SERPINB6 Polyclonal Antibody | G-AB-12447 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin (ov) -serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cell Biology

Synonyms: SERPINB6, CAP, DFNB91, MSTP057, PI-6, PI6, PTI, SPI3, serpin B6

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 5269

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human SERPINB6 (NP_004559.4) .

Clone #:

Conjugation: Unconjugated

Swissprot: P35237

Santa Cruz:

Calculated MW: 42 kDa

Observed MW: 43 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SERPINB6 Polyclonal Antibody DataSheet