STAT6 Polyclonal Antibody | G-AB-07230

STAT6 Polyclonal Antibody | G-AB-07230 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X (L) , which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms: D12S1644, IL-4-STAT, STAT6B, STAT6C, STAT6

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 6778

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human STAT6 (NP_001171550.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P42226

Santa Cruz:

Calculated MW: 74 kDa/81 kDa/94 kDa

Observed MW: 110 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

STAT6 Polyclonal Antibody DataSheet