STRADA Polyclonal Antibody | G-AB-06149

STRADA Polyclonal Antibody | G-AB-06149 | Gentaur Antibodies

Overview: The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25) . The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Metabolism, Immunology

Synonyms: Protein kinase LYK5, Serologically defined breast cancer antigen NY BR 96, STE20 related adapter protein, STRAD alpha, STRAD

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC043641

Clonality: Polyclonal

Immunogen: Full length fusion protein

Clone #:

Conjugation: Unconjugated

Swissprot: Q7RTN6

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1.5 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:45-1:300, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

STRADA Polyclonal Antibody DataSheet