TLR4 Polyclonal Antibody | G-AB-10567
Gentaur Antibodies
- SKU:
- G-AB-10567
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
TLR4 Polyclonal Antibody | G-AB-10567 | Gentaur Antibodies
Overview: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in Signal Transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular, Immunology, Microbiology
Synonyms: TLR4, ARMD10, CD284, TLR-4, TOLL
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 7099
Accession #:
Clonality:
Immunogen: A synthetic peptide of human TLR4 (NP_612564.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: O00206
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IHC, IF
Dilution: IHC 1:100-1:200 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.