TLR4 Polyclonal Antibody | G-AB-10567

TLR4 Polyclonal Antibody | G-AB-10567 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in Signal Transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Immunology, Microbiology

Synonyms: TLR4, ARMD10, CD284, TLR-4, TOLL

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 7099

Accession #:

Clonality:

Immunogen: A synthetic peptide of human TLR4 (NP_612564.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: O00206

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:100-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

TLR4 Polyclonal Antibody DataSheet