TriMethyl-Histone H4-K20 Polyclonal Antibody | G-AB-10060

TriMethyl-Histone H4-K20 Polyclonal Antibody | G-AB-10060 | Gentaur Antibodies

Overview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.

Category Type: Methylated antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: FO108, H4, H4/n, H4F2, H4FN, HIST2H4, Histone H4, HIST1H4A, HIST2H4A

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 8370

Accession #:

Clonality:

Immunogen: A synthetic methylated peptide corresponding to residues surrounding K20 of human histone H4

Clone #:

Conjugation: Unconjugated

Swissprot: P62805

Santa Cruz:

Calculated MW: 11 kDa

Observed MW: 11 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

TriMethyl-Histone H4-K20 Polyclonal Antibody DataSheet