UNC13B Polyclonal Antibody | G-AB-06256

UNC13B Polyclonal Antibody | G-AB-06256 | Gentaur Antibodies

Overview: This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.

Category Type: Polyclonal Antibody

Research Areas: Neuroscience, Signal Transduction

Synonyms: hmunc13, MGC133279, MGC133280, munc13, Munc13-2, Protein unc-13 homolog B, UN13B, unc-13 homolog B (C. elegans) , UNC13, Unc13b, Unc13h2

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC111781

Clonality: Polyclonal

Immunogen: Fusion protein of human UNC13B

Clone #:

Conjugation: Unconjugated

Swissprot: O14795

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1.5 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

UNC13B Polyclonal Antibody DataSheet