VEGF Receptor 1 Polyclonal Antibody | G-AB-10733

VEGF Receptor 1 Polyclonal Antibody | G-AB-10733 | Gentaur Antibodies

Overview: This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig) -like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms: FLT, FLT-1, VEGFR-1, VEGFR1, FLT1

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 2321

Accession #:

Clonality:

Immunogen: A synthetic peptide of human VEGF Receptor 1

Clone #:

Conjugation: Unconjugated

Swissprot: P17948

Santa Cruz:

Calculated MW: 39 kDa/41 kDa/52- 82 kDa/150 kDa

Observed MW: 180 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:1000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

VEGF Receptor 1 Polyclonal Antibody DataSheet