C8orf4 Polyclonal Antibody | G-AB-10994

C8orf4 Polyclonal Antibody | G-AB-10994 | Gentaur Antibodies

Overview: This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction, Stem cells

Synonyms: C8orf4, TC-1, TC1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 56892

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human C8orf4 (NP_064515.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9NR00

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

C8orf4 Polyclonal Antibody DataSheet