Cathepsin L Polyclonal Antibody | G-AB-00475

Cathepsin L Polyclonal Antibody | G-AB-00475 | Gentaur Antibodies

Overview: The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Neuroscience, Signal Transduction

Synonyms: cathepsin L, 1 b, Cathepsin L1, Cathepsin L1 light chain, CathepsinL, CATL, CATL1, cb15, CTSL, CTSL1, ctsl1b, FLJ31037, hgg1, Major excreted protein, MEP, MGC123162, wu:fb30g09

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC012612

Clonality: Polyclonal

Immunogen: Recombinant protein of human CTSL

Clone #:

Conjugation: Unconjugated

Swissprot: P07711

Santa Cruz: sc-6500/sc-6498/sc-10778/sc-25537

Calculated MW:

Observed MW:

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Cathepsin L Polyclonal Antibody DataSheet