CBX3 Monoclonal Antibody | G-AB-05730
- 3 to 5 Working Days
- Human, Mouse, Rat
CBX3 Monoclonal Antibody | G-AB-05730 | Gentaur Antibodies
Overview: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks.
Category Type: Monoclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Synonyms: CBX 3, CBX3, CBX3, Chromobox homolog 3 (HP1 gamma homolog, Drosophila) , Chromobox homolog 3, Chromobox protein homolog 3, GAMMA, HECH, Heterochromatin like protein 1, Heterochromatin protein 1 homolog gamma, Heterochromatin protein HP1 gamma, HP1 gamma, HP1 gamma homolog, HP1Hs gamma, Modifier 2 protein
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant Protein of HP-1γ
Clone #: Clone:4F4
Observed MW: 24 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification method: Protein A purification
Application: WB, IHC-p
Dilution: WB 1:500-2000, IHC 1:50-300
Storage: Store at -20°C. Avoid freeze / thaw cycles.