Cell Biology Antibody

PDCD4 Polyclonal Antibody | G-AB-00297 | Gentaur AntibodiesOverview: Programmed cell death 4 (Pdcd4) is a novel tumor suppressor that inhibits translation, progression and invasion. It was first identified as being differnetially upregulated during...

AKT1S1 Polyclonal Antibody | G-AB-00283 | Gentaur AntibodiesOverview: AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated.Category Type: Polyclonal AntibodyResearch Areas: Cancer,...

TIMP1 Polyclonal Antibody | G-AB-00280 | Gentaur AntibodiesOverview: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs) , a group of peptidases involved in...

BBC3 Polyclonal Antibody | G-AB-00269 | Gentaur AntibodiesOverview: This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to...

Cyclin A2 Polyclonal Antibody | G-AB-00263 | Gentaur AntibodiesOverview: CCNA2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as...

NFκB-p65 Polyclonal Antibody | G-AB-00262 | Gentaur AntibodiesOverview: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of...

KLK6 Polyclonal Antibody | G-AB-00253 | Gentaur AntibodiesOverview: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have...

KLK10 Polyclonal Antibody | G-AB-00252 | Gentaur AntibodiesOverview: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have...

KLK10 Polyclonal Antibody | G-AB-00251 | Gentaur AntibodiesOverview: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have...

PTEN Polyclonal Antibody | G-AB-00243 | Gentaur AntibodiesOverview: PTEN (also designated MMAC1) , products of tumor suppressor genes, are found deleted in most human gliomas. The PTEN genes are also mutated in many other tumors, such as brain, breast,...

BRCA1 Polyclonal Antibody | G-AB-00241 | Gentaur AntibodiesOverview: RCA1, also named as RNF53, plays a central role in DNA repair by facilitating cellular response to DNA repair. It is required for appropriate cell cycle arrests after ionizing...

p16 Polyclonal Antibody | G-AB-00224 | Gentaur AntibodiesOverview: This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of...

Lamin B1 Polyclonal Antibody | G-AB-00217 | Gentaur AntibodiesOverview: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly...

AIFM1 Polyclonal Antibody | G-AB-00215 | Gentaur AntibodiesOverview: This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis...

RAN Polyclonal Antibody | G-AB-00212 | Gentaur AntibodiesOverview: RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore...

ANXA5 Polyclonal Antibody | G-AB-00209 | Gentaur AntibodiesOverview: Annexin A5 (ANXA5) , is a member of the structurally related family of annexin proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic...

RAF1 Polyclonal Antibody | G-AB-00202 | Gentaur AntibodiesOverview: This gene is the cellular homolog of viral raf gene (v-raf) . The encoded protein is a MAP kinase kinase kinase (MAP3K) , which functions downstream of the Ras family of membrane...

NEDD8 Polyclonal Antibody | G-AB-00200 | Gentaur AntibodiesOverview: NEDD8 (neural precursor cell expressed, developmentally down-regulated 8) is a protein-coding gene. Diseases associated with NEDD8 include glomuvenous malformation. GO annotations...

STIL Polyclonal Antibody | G-AB-00197 | Gentaur AntibodiesOverview: This gene encodes a cytoplasmic protein implicated in regulation of the mitotic spindle checkpoint, a regulatory pathway that monitors chromosome segregation during cell division to...

UMOD Polyclonal Antibody | G-AB-00192 | Gentaur AntibodiesOverview: The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of...

JNK2 Polyclonal Antibody | G-AB-00188 | Gentaur AntibodiesOverview: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of...

S100B Polyclonal Antibody | G-AB-00185 | Gentaur AntibodiesOverview: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a...

MMP3 Polyclonal Antibody | G-AB-00180 | Gentaur AntibodiesOverview: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development,...

HSF27 Polyclonal Antibody | G-AB-00175 | Gentaur AntibodiesOverview: This gene encodes a protein that has been reported to function in signaling pathways governing transcriptional regulation and cell cycle progression. It may play a role in tumorigenesis...

CYCS Polyclonal Antibody | G-AB-00170 | Gentaur AntibodiesOverview: Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into...

DRP1 Polyclonal Antibody | G-AB-00166 | Gentaur AntibodiesOverview: This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated...

ANXA5 Polyclonal Antibody | G-AB-00163 | Gentaur AntibodiesOverview: Annexin A5 (ANXA5) , is a member of the structurally related family of annexin proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic...

SDHA Polyclonal Antibody | G-AB-00159 | Gentaur AntibodiesOverview: This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded...

SAT1 Polyclonal Antibody | G-AB-00158 | Gentaur AntibodiesOverview: Spermidine/spermine N1-acetyltransferase 1 (SAT1 or SSAT1) is the key regulatory enzyme in the catabolism of polyamines, catalyzing acetylation of spermidine or spermine to generate...

MAP2K6 Polyclonal Antibody | G-AB-00153 | Gentaur AntibodiesOverview: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular...

TIMP4 Polyclonal Antibody | G-AB-00149 | Gentaur AntibodiesOverview: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the...

MMP1 Polyclonal Antibody | G-AB-00143 | Gentaur AntibodiesOverview: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs) . Proteins in this family are involved in the breakdown of extracellular matrix in normal...

BAP1 Polyclonal Antibody | G-AB-00129 | Gentaur AntibodiesOverview: Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A and HCFC1. Catalytic component of the PR-DUB complex, a complex that specifically...

SERPINE1 Polyclonal Antibody | G-AB-00127 | Gentaur AntibodiesOverview: Serine protease inhibitor. This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function...

P73 Polyclonal Antibody | G-AB-00126 | Gentaur AntibodiesOverview: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the...

CASP12 Polyclonal Antibody | G-AB-00125 | Gentaur AntibodiesOverview: Has no protease activity. May reduce cytokine release in response to bacterial lipopolysaccharide during infections. Reduces activation of NF-kappa-B in response to TNF.Category Type:...

BCL2L15 Polyclonal Antibody | G-AB-00123 | Gentaur AntibodiesOverview: BCL2L15 (BCL2 Like 15) is a Protein Coding gene. Among its related pathways are Regulation of Apoptosis by Parathyroid Hormone-related Protein.Category Type: Polyclonal...

MMP13 Polyclonal Antibody | G-AB-00121 | Gentaur AntibodiesOverview: Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and...

TNFSF13B Polyclonal Antibody | G-AB-00120 | Gentaur AntibodiesOverview: Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation...

FAS Polyclonal Antibody | G-AB-00101 | Gentaur AntibodiesOverview: Fas (CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) receptor superfamily. It can mediates apoptosis by ligation with an agonistic anti-Fas...

MAPK13 Polyclonal Antibody | G-AB-00082 | Gentaur AntibodiesOverview: MAPK13 (Mitogen-activated protein kinase 13) is also named as PRKM13, SAPK4 and belongs to the protein kinase superfamily. MAPK13 is one of the four p38 MAPKs which play an important...

STK4 Polyclonal Antibody | G-AB-00073 | Gentaur AntibodiesOverview: The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein...

ALPL Polyclonal Antibody | G-AB-00069 | Gentaur AntibodiesOverview: A phosphate monoester + H2O = an alcohol + phosphate.Category Type: Polyclonal AntibodyResearch Areas: Cancer, Cell Biology, Tags & Cell MarkersSynonyms: AKP2, Alkaline phosphatase...

CDC40 Polyclonal Antibody | G-AB-00067 | Gentaur AntibodiesOverview: Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing.Category Type: Polyclonal AntibodyResearch Areas: Cancer, Cell...

SEPT5 Polyclonal Antibody | G-AB-00064 | Gentaur AntibodiesOverview: Filament-forming cytoskeletal GTPase (By similarity) . May play a role in cytokinesis (Potential) . May play a role in platelet secretion (By similarity) .Category Type: Polyclonal...

PARP3 Polyclonal Antibody | G-AB-00062 | Gentaur AntibodiesOverview: Involved in the base excision repair (BER) pathway, by catalyzing the poly (ADP-ribosyl) ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA...

PCLAF Polyclonal Antibody | G-AB-00061 | Gentaur AntibodiesOverview: PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between...

PDIA5 Polyclonal Antibody | G-AB-00060 | Gentaur AntibodiesOverview: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the...

EEF1E1 Polyclonal Antibody | G-AB-00059 | Gentaur AntibodiesOverview: Positive modulator of ATM response to DNA damage.Category Type: Polyclonal AntibodyResearch Areas: Cancer, Cell BiologySynonyms: AIMP 3, AIMP3, Aminoacyl tRNA synthetase complex...

ANXA5 Polyclonal Antibody | G-AB-00058 | Gentaur AntibodiesOverview: This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.Category Type:...

ANXA5 Polyclonal Antibody | G-AB-00057 | Gentaur AntibodiesOverview: This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.Category Type:...

CST5 Polyclonal Antibody | G-AB-00055 | Gentaur AntibodiesOverview: Cysteine proteinase inhibitor that possibly plays a protective role against proteinases present in the oral cavity. The order of preference for inhibition is cathepsin S > cathepsin H >...

P21 Polyclonal Antibody | G-AB-00054 | Gentaur AntibodiesOverview: May be involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of...

CDK2 Polyclonal Antibody | G-AB-00053 | Gentaur AntibodiesOverview: Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis.Category Type: Polyclonal AntibodyResearch Areas: Cancer,...

SDHA Polyclonal Antibody | G-AB-00052 | Gentaur AntibodiesOverview: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from...

TGM2 Polyclonal Antibody | G-AB-00051 | Gentaur AntibodiesOverview: Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.Category Type: Polyclonal AntibodyResearch Areas: Cancer, Cell Biology, Metabolism, Immunology,...

UQCRFS1 Polyclonal Antibody | G-AB-00049 | Gentaur AntibodiesOverview: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) , which is a respiratory chain that generates an electrochemical potential coupled...

CASP2 Polyclonal Antibody | G-AB-00048 | Gentaur AntibodiesOverview: Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins...

CDK1 Polyclonal Antibody | G-AB-00045 | Gentaur AntibodiesOverview: CDK1, also named as CDC2, belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family and CDC2/CDKX subfamily.CDC2 plays a key role in the control of the eukaryotic...

PBK Polyclonal Antibody | G-AB-00041 | Gentaur AntibodiesOverview: PBK (PDZ-binding kinase) is also named as TOPK, CT84, Nori-3, SPK and belongs to the MAP kinase kinase subfamily. PBK may have a role in the regulation of cellular proliferation and...

PCNA Polyclonal Antibody | G-AB-00038 | Gentaur AntibodiesOverview: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation...

SOD1 Polyclonal Antibody | G-AB-00031 | Gentaur AntibodiesOverview: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.Category Type: Polyclonal AntibodyResearch Areas: Cancer, Cell Biology,...

AIMP2 Polyclonal Antibody | G-AB-00030 | Gentaur AntibodiesOverview: Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC...

RELB Polyclonal Antibody | G-AB-00029 | Gentaur AntibodiesOverview: RELB, also named as Transcription factor RelB, is a 579 amino acid protein, which contains one RHD domain.RELB localizes in the nucleus and cytoplasm. RELB is a pleiotropic transcription...

S100B Polyclonal Antibody | G-AB-00023 | Gentaur AntibodiesOverview: S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs and has been implicated in the regulation of cellular activities such as metabolism,...

Metallothionein Polyclonal Antibody | G-AB-00019 | Gentaur AntibodiesOverview: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and...

CST3 Polyclonal Antibody | G-AB-00008 | Gentaur AntibodiesOverview: As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. Known to inhibit cathepsin B, H,...