DCTN4 Polyclonal Antibody | G-AB-02427
Gentaur Antibodies
- SKU:
- G-AB-02427
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
DCTN4 Polyclonal Antibody | G-AB-02427 | Gentaur Antibodies
Overview: Dynactin is a multisubunit complex and a required cofactor for most, or all, of the cellular processes powered by the microtubule-based motor cytoplasmic dynein . Dynactin contains a short actin-related protein 1 (Arp1) filament with capZ at the barbed end and p62 at the pointed end . The p62 subunit is an integral component of 20 S dynactin with a highly conserved cysteine-rich motif that interacts directly with Arp1. Dynactin p62 has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin . In addition, Dynactin p62 is distributed in the nucleus at very high expression levels . Due to the structural composition of dynactin, the p62 subunit is implicated in Arp1 pointed-end binding and in linking dynein and dynactin to the cortical cytoskeleton.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Signal Transduction
Synonyms: DCTN 4, Dctn4, DCTN4, Dynactin 4 (p62) , Dynactin 4, Dynactin p62 subunit, Dynactin subunit 4, Dynactin subunit p62, Dynactin4, p62
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: BC026323
Clonality: Polyclonal
Immunogen: Recombinant protein of human DCTN4
Clone #:
Conjugation: Unconjugated
Swissprot: Q9UJW0
Santa Cruz: sc-12239/sc-12241/sc-25730
Calculated MW:
Observed MW:
Concentration: 0.6 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: IHC, ELISA
Dilution: IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.