DUSP5 Polyclonal Antibody | G-AB-07335

DUSP5 Polyclonal Antibody | G-AB-07335 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38) , which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: DUSP5, DUSP, HVH3

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 1847

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human DUSP5 (NP_004410.3) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q16690

Santa Cruz:

Calculated MW: 42 kDa

Observed MW: 42 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

DUSP5 Polyclonal Antibody DataSheet