GRAP Polyclonal Antibody | G-AB-03993

GRAP Polyclonal Antibody | G-AB-03993 | Gentaur Antibodies

Overview: This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: Grap, GRAP, GRB2 related adaptor protein, GRB2-related adapter protein, Growth factor receptor bound protein 2 related adaptor protein, MGC64880, OTTHUMP00000065766

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC035856

Clonality: Polyclonal

Immunogen: Full length fusion protein

Clone #:

Conjugation: Unconjugated

Swissprot: Q13588

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

GRAP Polyclonal Antibody DataSheet