INS (C-peptide) Polyclonal Antibody | G-AB-04827

INS (C-peptide) Polyclonal Antibody | G-AB-04827 | Gentaur Antibodies

Overview: Insulin is a peptide hormone, produced by beta cells of the pancreas, and is central to regulating carbohydrate and fat metabolism in the body. It participates in glucose utilization, protein synthesis and in the formation and storage of neutral lipids. Insulin is synthesized as a precursor molecule, proinsulin, which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form insulin, while the central portion of the precursor molecule is cleaved and released as the C-peptide. Defects in insulin results in type 1 diabetes mellitus. Insulin may also exist 36 kDa form corresponding to the hexameric insulin form.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction

Synonyms: IDDM, IDDM1, IDDM2, ILPR, ins, INS, Insulin A chain, Insulin B chain, IRDN, MODY10, Preproinsulin, Proinsulin, Proinsulin precursor

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP000198

Clonality: Polyclonal

Immunogen: Synthetic peptide of human INS (C-peptide)

Clone #:

Conjugation: Unconjugated

Swissprot: P01308

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1.08 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:100, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

INS (C-peptide) Polyclonal Antibody DataSheet