LMNA Polyclonal Antibody | G-AB-05909

LMNA Polyclonal Antibody | G-AB-05909 | Gentaur Antibodies

Overview: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction, Tags & Cell Markers

Synonyms: 70 kDa lamin, Cardiomyopathy dilated 1A (autosomal dominant) , CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, Lamin A, Lamin A/C, Lamin A/C like 1, Lamin, Lamin C, Lamin-A/C, LDP1, LFP, LGMD1B, Limb girdle muscular dystrophy 1B (autosomal dominant) , LMN 1, LMN A, LMN C, LMN1, LMNA, LMNA, LMNC, LMNL1, Prelamin A/C, PRO1, Renal carcinoma antigen NY REN 32, Renal carcinoma antigen NY-REN-32, Renal carcinoma antigen NYREN32

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human Lamin A/C around the non-phosphorylation site of Ser392.

Clone #:

Conjugation: Unconjugated

Swissprot: P02545

Santa Cruz:

Calculated MW: 74 kDa

Observed MW: 74 kDa, 65 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification method: Affinity purification

Application: WB, IHC-p, IF, ELISA

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

LMNA Polyclonal Antibody DataSheet