LRP6 Polyclonal Antibody | G-AB-08920
Gentaur Antibodies
Write a Review
Gentaur Antibodies
LRP6 Polyclonal Antibody | G-AB-08920
- SKU:
- G-AB-08920
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
LRP6 Polyclonal Antibody | G-AB-08920 | Gentaur Antibodies
Overview: This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Signal Transduction, Stem cells
Synonyms: LRP6, ADCAD2, STHAG7
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID: 4040
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human LRP6 (NP_002327.2) .
Clone #:
Conjugation: Unconjugated
Swissprot: O75581
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IF
Dilution: IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Related Products
