Mineralocorticoid receptor Polyclonal Antibody | G-AB-05403

Mineralocorticoid receptor Polyclonal Antibody | G-AB-05403 | Gentaur Antibodies

Overview: This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction, Cardiovascular, Epigenetics and Nuclear Signaling

Synonyms: Aldosterone receptor, MCR, MGC133092, Mineralocorticoid receptor, MLR, MR, NR3 C2, NR3C2, NR3C2 protein, Nuclear receptor subfamily 3 group C member 2

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Mineralocorticoid receptor

Clone #:

Conjugation: Unconjugated

Swissprot: P08235, Q8VII8, P22199

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1.3 mg/mL

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:200-1:800

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Mineralocorticoid receptor Polyclonal Antibody DataSheet