Mineralocorticoid receptor Polyclonal Antibody | G-AB-05403
- 3 to 5 Working Days
- Human, Mouse, Rat
Mineralocorticoid receptor Polyclonal Antibody | G-AB-05403 | Gentaur Antibodies
Overview: This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.
Category Type: Polyclonal Antibody
Research Areas: Signal Transduction, Cardiovascular, Epigenetics and Nuclear Signaling
Synonyms: Aldosterone receptor, MCR, MGC133092, Mineralocorticoid receptor, MLR, MR, NR3 C2, NR3C2, NR3C2 protein, Nuclear receptor subfamily 3 group C member 2
Reactivity: Human, Mouse, Rat
Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Mineralocorticoid receptor
Swissprot: P08235, Q8VII8, P22199
Concentration: 1.3 mg/mL
Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Purification method: Affinity purification
Dilution: IHC 1:200-1:800
Storage: Store at -20°C. Avoid freeze / thaw cycles.