PD-L1 Polyclonal Antibody | G-AB-07518

PD-L1 Polyclonal Antibody | G-AB-07518 | Gentaur Antibodies

Overview: This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Immunology

Synonyms: B7-H, B7H1, PDL1, PD-L1, PDCD1L1, PDCD1LG1, CD274

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 29126

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human PD-L1 (NP_054862.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9NZQ7

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PD-L1 Polyclonal Antibody DataSheet