Phospho-HDAC5 (S498) Polyclonal Antibody | G-AB-12532
Gentaur Antibodies
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Gentaur Antibodies
Phospho-HDAC5 (S498) Polyclonal Antibody | G-AB-12532
- SKU:
- G-AB-12532
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
Phospho-HDAC5 (S498) Polyclonal Antibody | G-AB-12532 | Gentaur Antibodies
Overview: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.
Category Type: Phosphorylated antibody
Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Stem Cells
Synonyms: HDAC5, HD5, NY-CO-9
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 10014
Accession #:
Clonality:
Immunogen: A phospho specific peptide corresponding to residues surrounding S498 of human HDAC5
Clone #:
Conjugation: Unconjugated
Swissprot: Q9UQL6
Santa Cruz:
Calculated MW: 112 kDa/121 kDa/122 kDa
Observed MW: 140 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IHC
Dilution: WB 1:500-1:2000 IHC 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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