Phospho-MAP2K1 (pS221) Polyclonal Antibody | G-AB-12493
- 3 to 5 Working Days
- Human, Mouse, Rat
Phospho-MAP2K1 (pS221) Polyclonal Antibody | G-AB-12493 | Gentaur Antibodies
Overview: The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs) , act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase Signal Transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
Category Type: Phosphorylated antibody
Research Areas: Cancer, Signal Transduction
Synonyms: CFC3, MAPKK1, MEK1, MKK1, PRKMK1, MAP2K1
Reactivity: Human, Mouse, Rat
Gene ID: 5604
Immunogen: A synthetic phosphorylated peptide around S221 of human MAP2K1 (NP_002746.1) .
Calculated MW: 40 kDa/43 kDa
Observed MW: 43 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.