Phospho-MAP2K1 (pS221) Polyclonal Antibody | G-AB-12493

Phospho-MAP2K1 (pS221) Polyclonal Antibody | G-AB-12493 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs) , act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase Signal Transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.

Category Type: Phosphorylated antibody

Research Areas: Cancer, Signal Transduction

Synonyms: CFC3, MAPKK1, MEK1, MKK1, PRKMK1, MAP2K1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 5604

Accession #:

Clonality:

Immunogen: A synthetic phosphorylated peptide around S221 of human MAP2K1 (NP_002746.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q02750

Santa Cruz:

Calculated MW: 40 kDa/43 kDa

Observed MW: 43 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Phospho-MAP2K1 (pS221) Polyclonal Antibody DataSheet