Phospho-PKCalpha/beta II (T638/641) Polyclonal Antibody | G-AB-12531

Phospho-PKCalpha/beta II (T638/641) Polyclonal Antibody | G-AB-12531 | Gentaur Antibodies

Overview: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Category Type: Phosphorylated antibody

Research Areas:

Synonyms: PKC-beta, PKCB, PRKCB1, PRKCB2

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 5578/5579

Accession #:

Clonality:

Immunogen: A phospho specific peptide corresponding to residues surrounding T641 of human PRKCB

Clone #:

Conjugation: Unconjugated

Swissprot: P17252, P05771

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:100 IF 1:100-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Phospho-PKCalpha/beta II (T638/641) Polyclonal Antibody DataSheet