Phospho-PKCalpha (S319) Polyclonal Antibody | G-AB-12599

Phospho-PKCalpha (S319) Polyclonal Antibody | G-AB-12599 | Gentaur Antibodies

Overview: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca (2+) handling in myocytes.

Category Type: Phosphorylated antibody

Research Areas: Cancer, Cardiovascular, Signal Transduction

Synonyms: PRKCA, AAG6, PKC-alpha, PKCA, PRKACA, PKC alpha

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 5578

Accession #:

Clonality:

Immunogen: A synthetic phosphorylated peptide around S319 of human PKCalpha (NP_002728.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P17252

Santa Cruz:

Calculated MW: 76 kDa

Observed MW: 100 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Phospho-PKCalpha (S319) Polyclonal Antibody DataSheet