PLS3 Polyclonal Antibody | G-AB-10355

PLS3 Polyclonal Antibody | G-AB-10355 | Gentaur Antibodies

Overview: Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.) . The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction

Synonyms: PLS3, BMND18, T-plastin, plastin-3

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 5358

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human PLS3 (NP_005023.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P13797

Santa Cruz:

Calculated MW: 65 kDa/69 kDa/70 kDa

Observed MW: 71 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:200-1:2000 IHC 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PLS3 Polyclonal Antibody DataSheet