SDHB Polyclonal Antibody | G-AB-07447

SDHB Polyclonal Antibody | G-AB-07447 | Gentaur Antibodies

Overview: Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell biology, Metabolism, Signal Transduction

Synonyms: SDHB, CWS2, IP, PGL4, SDH, SDH1, SDH2, SDHIP

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 6390

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human SDHB (NP_002991.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P21912

Santa Cruz:

Calculated MW: 31 kDa

Observed MW: 32 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000 IHC 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SDHB Polyclonal Antibody DataSheet