Epigenetics & Nuclear Signaling Research

Acetyl-DNMT1-K1127/K1129/K1131/K1133 Polyclonal Antibody | G-AB-10726 | Gentaur AntibodiesOverview: This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for...

(KO Validated) DNMT1 Polyclonal Antibody | G-AB-10690 | Gentaur AntibodiesOverview: This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation...

(KO Validated) LITAF Polyclonal Antibody | G-AB-10673 | Gentaur AntibodiesOverview: Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators...

Acetyl-Histone H4-K16 Polyclonal Antibody | G-AB-10575 | Gentaur AntibodiesOverview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately...

OTUD7B Polyclonal Antibody | G-AB-10534 | Gentaur AntibodiesOverview: OTUD7B (OTU Deubiquitinase 7B) is a Protein Coding gene. Diseases associated with OTUD7B include Autoinflammation, Panniculitis, And Dermatosis Syndrome. Among its related pathways are...

UBE2L6 Polyclonal Antibody | G-AB-10457 | Gentaur AntibodiesOverview: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three...

Symmetric DiMethyl-Histone H4-R3 Polyclonal Antibody | G-AB-10285 | Gentaur AntibodiesOverview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of...

Symmetric DiMethyl-Histone H3-R26 Polyclonal Antibody | G-AB-10280 | Gentaur AntibodiesOverview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the...

Symmetric DiMethyl-Histone H3-R17 Polyclonal Antibody | G-AB-10279 | Gentaur AntibodiesOverview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the...

MonoMethyl-Histone H3-R17 Polyclonal Antibody | G-AB-10278 | Gentaur AntibodiesOverview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core...

(KO Validated) APEX1 Polyclonal Antibody | G-AB-10147 | Gentaur AntibodiesOverview: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal...

(KO Validated) PDCD4 Polyclonal Antibody | G-AB-10132 | Gentaur AntibodiesOverview: This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding...

(KO Validated) HMGB1 Polyclonal Antibody | G-AB-10121 | Gentaur AntibodiesOverview: This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is...

Asymmetric DiMethyl-Histone H3-R17 Polyclonal Antibody | G-AB-10067 | Gentaur AntibodiesOverview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the...

PDCD4 Polyclonal Antibody | G-AB-10066 | Gentaur AntibodiesOverview: This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative...

Asymmetric DiMethyl-Histone H4-R3 Polyclonal Antibody | G-AB-10064 | Gentaur AntibodiesOverview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of...

Asymmetric DiMethyl-Histone H3-R26 Polyclonal Antibody | G-AB-10063 | Gentaur AntibodiesOverview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the...

TriMethyl-Histone H4-K20 Polyclonal Antibody | G-AB-10060 | Gentaur AntibodiesOverview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately...

DiMethyl-Histone H4-K20 Polyclonal Antibody | G-AB-10059 | Gentaur AntibodiesOverview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately...

MonoMethyl-Histone H4-K20 Polyclonal Antibody | G-AB-10058 | Gentaur AntibodiesOverview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of...

(KO Validated) CBX3 Polyclonal Antibody | G-AB-10025 | Gentaur AntibodiesOverview: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component...

(KO Validated) CTCF Polyclonal Antibody | G-AB-09800 | Gentaur AntibodiesOverview: This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear...

(KO Validated) UBE2S Polyclonal Antibody | G-AB-09744 | Gentaur AntibodiesOverview: This gene encodes a member of the ubiquitin-conjugating enzyme family. The encoded protein is able to form a thiol ester linkage with ubiquitin in a ubiquitin activating...

Acetyl-Histone H3-K9/K14/K18/K23/K27 Polyclonal Antibody | G-AB-09733 | Gentaur AntibodiesOverview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of...

MDM4 Polyclonal Antibody | G-AB-09704 | Gentaur AntibodiesOverview: This gene encodes a nuclear protein that contains a p53 binding domain at the N-terminus and a RING finger domain at the C-terminus, and shows structural similarity to p53-binding...

(KO Validated) HuR / ELAVL1 Polyclonal Antibody | G-AB-09306 | Gentaur AntibodiesOverview: The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich...

MonoMethyl-UHRF1-K385 Polyclonal Antibody | G-AB-09270 | Gentaur AntibodiesOverview: This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to...

Acetyl-Histone H2A-K5 Polyclonal Antibody | G-AB-09114 | Gentaur AntibodiesOverview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core...

Acetyl-Histone H2B-K12 Polyclonal Antibody | G-AB-09112 | Gentaur AntibodiesOverview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core...

Acetyl-Histone H4-K5 Polyclonal Antibody | G-AB-09003 | Gentaur AntibodiesOverview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146...

(KO Validated) CHRAC1 Polyclonal Antibody | G-AB-08848 | Gentaur AntibodiesOverview: CHRAC1 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine...

Acetyl-Histone H4-K12 Polyclonal Antibody | G-AB-08616 | Gentaur AntibodiesOverview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core...

PRKDC Polyclonal Antibody | G-AB-08601 | Gentaur AntibodiesOverview: This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK) . It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and...

(KO Validated) NUDT1 Polyclonal Antibody | G-AB-08165 | Gentaur AntibodiesOverview: Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or...

(KO Validated) STAT3 Polyclonal Antibody | G-AB-07649 | Gentaur AntibodiesOverview: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the...

YAP1 Polyclonal Antibody | G-AB-07648 | Gentaur AntibodiesOverview: This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the...

(KO Validated) HNRNPA2B1 Polyclonal Antibody | G-AB-07589 | Gentaur AntibodiesOverview: This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they...

(KO Validated) SQSTM1 / p62 Polyclonal Antibody | G-AB-07560 | Gentaur AntibodiesOverview: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein...

PTEN Monoclonal Antibody | G-AB-07488 | Gentaur AntibodiesOverview: This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol-3, 4,...

(KO Validated) EZH2 Polyclonal Antibody | G-AB-07478 | Gentaur AntibodiesOverview: This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional...

(KO Validated) NCOA2 Polyclonal Antibody | G-AB-07355 | Gentaur AntibodiesOverview: The protein encoded by this gene functions as a transcriptional coactivator for nuclear hormone receptors, including steroid, thyroid, retinoid, and vitamin D receptors...

(KO Validated) YAP1 Polyclonal Antibody | G-AB-07290 | Gentaur AntibodiesOverview: This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to...

(KO Validated) PARK7 Polyclonal Antibody | G-AB-07274 | Gentaur AntibodiesOverview: The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also...

(KO Validated) CCND3 Polyclonal Antibody | G-AB-07227 | Gentaur AntibodiesOverview: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through...